Herpesvirus Nuclear Egress across the Outer Nuclear Membrane
Herpesvirus capsids are assembled in the nucleus and undergo a two-step process to cross the nuclear envelope.Capsids bud into the inner nuclear membrane (INM) aided by the nuclear egress complex (NEC) proteins UL31/34.At that stage of egress, enveloped virions are found for a short time in the perinuclear space.In the second il barone wine step of